A standard mouse can cause wrist pain over time, especially if you're using one for eight or more hours a day. Ergonomic mice and trackballs are shaped to keep your hand and wrist in a more natural position, reducing the strain that leads to conditions like carpal tunnel syndrome. Vertical mice angle your grip into a handshake position, while trackballs eliminate the need to move your arm entirely. Key features to look for include adjustable DPI for precision, wireless connectivity to reduce desk clutter, and programmable buttons to speed up your workflow. Browse our picks for the best ergonomic mice and trackballs on the UK market.